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Table 1 SAA receptor interactions

From: Serum amyloid A – a review

Receptor

Function

References

SR-B1

Cholesterol efflux, clears SAA

Tomita et al. (2015); He et al. (2003, 2006); Ye and Sun (2017); van der Westhuyzen et al. (2005); Cai et al. (2005)

FPRL1

Stimulates MMP-9

Badolato et al. (1994, 1995); Gao and Murphy (1993); Fiore et al. (1994); Su et al. (1999); Patel et al. (1998); Furlaneto and Campa (2000); Dufton et al. (2010); Ji et al. (2015)

FPR2

Phagocyte migration; antiapoptotic

de Buck et al. (2016); Gao and Murphy (1993); Furlaneto and Campa (2000); Ye and Sun (2017); Chen et al. (2014)

TLR2

Induce IRZF7, IRF4-jmjd3; M2 markers (IL-33, IL-10, IL-1m)

de Buck et al. (2016); Ray et al. (2006); He et al. (2006, 2007); Cheng et al. (2008); Ji et al. (2015); Ye and Sun (2017); Rosenthal et al. (1976); Chen and Moller (2010)

TLR4

Activate NF-κB, AP-1→NOS

Hiratsuka et al. (2008); de Buck et al. (2016); Sandri et al. (2008); Deguchi et al. (2013); Li et al. (2015); Ye and Sun (2017); Poltorak et al. (1998)

RAGE

Activate NF-κB, induce cytokines

Li et al. (2015); Yan et al. (2000); Rὄcken et al. (2003); Kennel et al. (2016); Ye and Sun (2017)

Bacteria

Opsonize Gram negative species

Hari-Dass et al. (2005); Shah et al. (2006); Ye and Sun (2017)